Benjamin C Trumble, PhD
Associate Professor, Arizona State University
My research examines how environmental conditions like parasites, pathogens, food availability, and social interactions impact human health. Taking an evolutionary life history perspective, I use field and laboratory studies to understand variation in human endocrine and immune systems, and how these factors interact to influence chronic diseases of aging including benign prostatic hyperplasia, cardiovascular disease, and Alzheimer’s dementia. I co-direct the Tsimane Health and Life History Project. When not in the lab or in the field, I enjoy hiking, cooking, and playing with my dog Ace (short for the Angiotensin-converting enzyme 2 [ACE2] receptor), and cats Widget, Frodo, and Asheville.
Angela R Garcia, PhD
My research focuses on how social adversity impacts health disparities and disease risk. I use a life history framework and a multilevel systems biology approach to explore interactions between genetics, transcriptomics, cortisol, immune markers, perceptions, and behavior in order to understand the physiology of disparities in health within and between populations. My current projects are focused on evaluating the links between social adversity, endocrine-immune signaling, and metabolic and cognitive health among Honduran immigrants on the island of Utila, and the Tsimane and Moseten of Bolivia. Specifically, I am investigating the effects of changing social and ecological milieu on metabolic and cognitive risk through how parasitic infection moderates social influences on the expression of genes (mRNA) related to stress and inflammation.
I hold a Ph.D. in Biological Anthropology from the University of California Santa Barbara, and I am currently a postdoctoral research fellow at Arizona State University in the Center for Evolution and Medicine, working with Ben Trumble and Ken Buetow.
Stephanie Koebele, PhD
I hold a PhD in Behavioral Neuroscience in Psychology from Arizona State University. I am also an ASU undergraduate alumna with dual bachelor’s degrees in Psychology and Spanish. My doctoral research (funded by a predoctoral NRSA from the National Institute on Aging) focused on the neurobiological and cognitive impacts of hysterectomy and other variations in menopause using rodent models. As a postdoctoral scholar in the Trumble Lab, my research interests center on how reproductive hormone fluctuations across the lifespan, including pregnancy and menopause, interact with environmental and immune factors to influence brain and whole-body health during aging. I am especially interested in how sex differences, environmental conditions, and lived experiences contribute to the development of chronic diseases of aging, including Alzheimer’s disease. Outside of the lab, I enjoy live music, yoga, cooking, hiking, and traveling! Pronouns: she/her/hers
Previous Lab Members:
Sam Patterson (Grad Student)
Mia Charifson (Grad Student)
Kate Woolard (Grad Student)
Katelyn Dinkel (Undergraduate Student)